Abstract: The Lunar Reconnaissance Orbiter (LRO) has provided a vast amount of scientific data for lunar research and future lunar exploration missions, with the acquisition of its precise orbit being a prerequisite for other scientific studies. Based on the independently developed WUDOGS software, this paper performs precise orbit determination for LRO using S-band radio tracking data from the White Sands and USN stations, applying a high-precision solar radiation pressure model and high-gain antenna correction. A comparative analysis between the results of this study and the official precise orbit released by NASA GSFC indicates that, after applying a high-precision multi-panel model and high-gain antenna correction, the obtained precise orbit is comparable in accuracy to NASA GSFC’s post-processed precise orbit, with a positional discrepancy at the 10 m level and velocity accuracy at the 10 mm/s level.